A1Vacations is part of HomeAway.com, the world’s leading vacation rentals marketplace.
Search over 150,000 vacation rentals properties now!   Click here to see more Vacation Homes

Florida South Central Gulf Coast Rentals  See more Florida South Central Gulf Coast Rentals at HomeAway.com

Vacation rentals and condos in Florida’s South Central Gulf region are excellent lodging options for a vacation on the Gulf of Mexico. The South Central Gulf includes the vacation destinations Anna Maria Island, Cape Coral, Fort Myers, Fort Myers Beach, Gasparilla Island, Port Charlotte, Rotonda West, Captiva and Sanibel Islands, Sarasota, Venice and Siesta Key. Begin your search for South Central Gulf vacation villas, condo rentals, beach houses, bungalows and other accommodations by following the links above.

Featured Listings

  • Rotonda West

    Property Details
    • Florida South Central Gulf Coast, VILLA
    • 3 bedrooms, Sleeps 6

  • Fort Myers Beach

    Property Details
    • Florida South Central Gulf Coast, CONDO
    • 2 bedrooms, Sleeps 6

  • North Captiva Island

    Property Details
    • Florida South Central Gulf Coast, HOUSE
    • 3 bedrooms, Sleeps 8

  • Siesta Key

    Property Details
    • Florida South Central Gulf Coast, CONDO
    • 1 bedroom, Sleeps 4

  • Fort Myers Beach

    Property Details
    • Florida South Central Gulf Coast, CONDO
    • 2 bedrooms, Sleeps 6

Destinations

About Florida South Central Gulf Coast Vacation Rentals

A Florida South Central Gulf vacation rental is a great way to experience this fabulous beach vacation destination.

Guests of Anna Maria Island vacation rentals and beachfront condos can enjoy a seven-mile-long beach, fish from three piers, and play golf on 45 nearby golf courses.

Step out the door of your Sanibel Island beachfront condo or vacation rental and you’ll be on one of Florida's best shelling beaches. Guests of Sanibel Island villas and vacation rentals can relax on the white sand beach, walk, skate, or bike on miles of paved paths, and explore the 5,000-acre J.N. “Ding” Darling Wildlife Refuge. Nearby Captiva Island villas and vacation rentals are great for collecting seashells on the soft white sand beach, snorkeling, diving, fishing, and golfing.

Discover the charm of Fort Myers and Fort Myers Beach vacation rentals, with easy access to dozens of golf courses and lovely beaches. Attractions for guests of Fort Myers condos and vacation rentals include parasailing, fishing, snorkeling, diving, golfing, and dolphin watching.

Attractions for guests of Cape Coral vacation rentals and condos include the Sun Splash Family Waterpark, the Children's Science Center, the annual Festival of the Arts held in January, and variety of beach activities at nearby Sanibel, Captiva, and Fort Myers.

Guests of Siesta Key vacation rentals can enjoy plenty of beach activities on the white sand beaches of this eight-mile-long barrier island near Sarasota and explore the shops, restaurants, and nightlife of Siesta Village.

A Sarasota vacation rental makes a great home base for enjoying the city's fabulous white sand beaches and lively arts scene. Other attractions for guests of Sarasota condos and vacation rentals include the Sarasota Jungle Gardens, the Sarasota Classic Car Museum, and Cincinnati Reds spring training.

Guests of Venice and Venice Island condos and vacation rentals can enjoy the scenic beaches of this area and collect seashells and sharks teeth fossils on the beach. Other attractions for guests of Venice Island and Venice vacation rentals include fishing on the 750-foot pier and exploring the nature trail and canals.

Other popular Florida South Gulf Coast accommodations include Englewood, Gasparilla, and Rotonda West vacation rentals.

Make the most of your Florida South Central Gulf vacation – reserve your Florida luxury villa, vacation rental, or oceanfront condo today!